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69,208 articles from EurekAlert

• MONDAY 6. FEBRUARY, 2012
• 06:00 'ROCK' off: Study establishes molecular link between genetic defect and heart malformation

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  UNC researchers have discovered how the genetic defect underlying one of the most common congenital heart diseases keeps the critical organ from developing properly. According to the new research, mutations in a gene called SHP-2 distort the shape of cardiac muscle cells so they are unable to form a fully functioning heart. The study also shows that treatment with a drug that regulates cell shape rescues the cardiac defect.  

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• 06:00 'Test and Treat' model offers new strategy for eliminating malaria

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  Researchers found that actively identifying undiagnosed malaria and then treating those with the disease resulted in significantly lower prevalence of malaria cases compared to a control group.  

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• 06:00 3 'targeted' cancer drugs raise risk of fatal side effects

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  Treatment with three "targeted" cancer drugs has been linked to a slightly elevated chance of fatal side effects, according to a new analysis led by scientists at Dana-Farber Cancer Institute. The risk for the fatal side effects remains low, but they should be factored in when developing patients' treatment plans.  

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• 06:00 A bug's (sex) life: Diving beetles offer unexpected clues about sexual selection

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  Studies of diving beetles suggest sperm evolution may be driven by changes in female reproductive organs, challenging the paradigm of post-mating sexual selection being driven mostly by competition among sperm. In the process, the researchers discovered an unexpected and stunning variety of sperm form and behavior.  

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• 06:00 A new species of bamboo-feeding plant lice found in Costa Rica

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  Several periods of field work during 2008 have led to the discovery of a new species of bamboo-feeding plant lice in Costa Rica's high-altitude region Cerro de la Muerte. The discovery was made thanks to molecular data analysis of mitochondrial DNA. The collected records have also increased the overall knowledge of plant lice (one of the most dangerous agricultural pests worldwide) from the region with more that 20 percent. The study was published in the open-access journal ZooKeys.  

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• 06:00 ACP recommends metformin to treat type 2 diabetes based on CE analysis of oral medications

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  In a new clinical practice guideline for drug treatment of type 2 diabetes, the American College of Physicians recommends metformin to treat type 2 diabetes based on a comparative effectiveness analysis of oral medications.  

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• 06:00 Antidepressant-suicide link in youths absent in new analysis

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  In 2004, concerns about antidepressant drugs increasing suicidal thoughts and behaviors in young patients prompted the FDA to issue a rare "black box warning." Now, a new analysis of clinical trial data finds that treatment with the antidepressant fluoxetine did not increase -- or decrease -- suicidality in children compared to placebo treatment.  

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• 06:00 Behavioral prevention model appears to reduce bullying, peer rejection

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  A widely used universal behavioral prevention model in schools appears to be associated with lower rates of teacher-reported bullying and peer rejection, according to a report in the February issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.  

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• 06:00 Big jolt to state economy with new tax on cigarettes

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  A new UCSF analysis has found that a state ballot initiative to increase the cigarette tax would create about 12,000 jobs and nearly $2 billion in new economic activity in California.  

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• 06:00 Children hospitalized at alarming rate due to abuse

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  In one year alone, over 4,500 children in the United States were hospitalized due to child abuse, and 300 of them died of their injuries, Yale School of Medicine researchers report in a new study. The findings are published in the March 2012 issue of Pediatrics published online Feb. 6.  

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• 06:00 Cognitive problems common among non-demented elderly

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  Both subjective and objective cognitive impairment are highly common among non-demented elderly Swedes, with an overall prevalence of 39 percent and 25 percent respectively, according to a nationwide twin study by researchers at the Aging Research Center of Karolinska Institutet, Sweden. The study confirms higher education as a major protective factor and stresses the importance of environmental aspects over genes in mild cognitive disorders in old age.  

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• 06:00 Combined asthma medication therapy shown to reduce attacks

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  A Henry Ford Hospital study has found that using two types of common asthma medications in combination reduces severe asthma attacks.Researchers say using long-acting beta-agonists in fixed-dose combination with inhaled corticosteroid (ICS) appear to reduce asthma attacks as well as or better than corticosteroids alone. Patient groups who had in greatest benefits were patients 18 and older, African-American patients, male patients, and patients with moderate to severe asthma.  

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• 06:00 Combined oral contraceptive pill helps painful periods

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  A large Scandinavian study, that has been running for 30 years, has finally provided convincing evidence that the combined oral contraceptive pill does, indeed, alleviate the symptoms of painful menstrual periods reports scientists from the University of Gothenburg, Sweden.  

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• 06:00 Consumers willing to buy sustainable US cotton, MU researchers find

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  Researchers from the University of Missouri have found that United States consumers are more willing to buy clothing made from sustainably grown US cotton than apparel produced using conventional practices in an unknown location.  

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• 06:00 Copper + love chemical = big sulfur stink

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  When Hiroaki Matsunami, Ph.D., at Duke set out to study a chemical in male mouse urine called MTMT that attracts female mice, he didn't think he would stumble into a new field of study. But the research has led scientists at Duke University Medical Center and the University of Albany to the discovery that it's the copper in our bodies that makes mammals recoil from sulfur chemical smells.  

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• 06:00 Discovery predicts patient sensitivity to important drug target in deadly brain cancer

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  A recent discovery by Van Andel Research Institute scientists enables the prediction of patient sensitivity to proposed drug therapies for glioblastoma - the most common and most aggressive malignant brain tumor in humans.  

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• 06:00 Do patients pay when they leave against medical advice?

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  There are ways in which patients who leave the hospital against medical advice wind up paying for that decision. Being saddled with the full cost of their hospital stay, however, is not one of them.  

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• 06:00 Does online dating really work?

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  Whether enlisting the help of a grandmother or a friend or the magic of Cupid, singles long have understood that assistance may be required to meet someone special. Today such help is likely to come from online methods of matchmaking. But online dating, according to new Northwestern University research, depends largely on ineffective algorithms and profiles for finding potential love interests. Mobile dating, the latest iteration in digital dating, however, may hold the most promise.  

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• 06:00 Domestic cats, and wild bobcats and pumas, living in same area have same diseases

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  The joint National Science Foundation and National Institutes of Health Ecology and Evolution of Infectious Diseases Program funded the study. Scientists at Colorado State University and other institutions conducted the research. It provides evidence that domestic cats and wild cats that share the same outdoor areas in urban environments also can share diseases such as Bartonellosis and Toxoplasmosis. Both can be spread from cats to people.  

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• 06:00 Drugs targeting chromosomal instability may fight a particular breast cancer subtype

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  A team of researchers at Jefferson's Kimmel Cancer Center led by Richard G. Pestell, M.D., PhD., FACP, Director of the KCC and Chair of the Department of Cancer Biology, have shown in a study published online Feb. 6 in the Journal of Clinical Investigation that the oncogene cyclin D1 may promote a genetic breakdown known as chromosomal instability.  

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• 06:00 East views the world differently to West

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  Cultural differences between the West and East are well documented, but a study shows that concrete differences also exist in how British and Chinese people recognize people and the world around them. Easterners really do look at the world differently to Westerners, according to new research funded by the Economic and Social Research Council.  

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• 06:00 Easy-to-use blood thinners likely to replace Coumadin

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  Within a few years, a new generation of easy-to-use blood-thinning drugs will likely replace Coumadin for patients with irregular heartbeats who are at risk for stroke, according to a journal article by Loyola University Medical Center physicians.  

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• 06:00 Embargoed news for Annals of Internal Medicine

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  Below is information about articles being published in the Feb. 7 issue of Annals of Internal Medicine. The information is not intended to substitute for the full articles as sources of information. Annals of Internal Medicine attribution is required for all coverage.  

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• 06:00 Exercise triggers stem cells in muscle

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  University of Illinois researchers determined that an adult stem cell present in muscle is responsive to exercise, a discovery that may provide a link between exercise and muscle health. The findings could lead to new therapeutic techniques using these cells to rehabilitate injured muscle and prevent or restore muscle loss with age.  

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• 06:00 First-trimester induced abortion not associated with increased risk of psychiatric readmission

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  First-time first-trimester induced abortion is not associated with an increased risk of readmission to psychiatric facilities among women with a history of a treated mental disorder, according to a report in the February issue of Archives of General Psychiatry, one of the JAMA/Archives journals.  

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