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271 articles from TUESDAY 3.1.2012
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TUESDAY 3. JANUARY, 2012
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06:00
Anti-sense might make sense for treating liver cancer
A new study shows that it is possible to selectively target and block a particular microRNA that is important in liver cancer. The findings might offer a new therapy for this malignancy, which kills an estimated 549,000 people worldwide annually. The study focused on miR-221, which is consistently present at abnormally high levels in human liver cancer. The treatment significantly prolonged survival in an animal model and promoted the activity of important tumor-suppressor genes. -
06:00To reduce mortality and improve patient care in the nation's ICUs, a task force formed by the Critical Care Societies Collaborative, in conjunction with the US Critical Illness and Injury Trials Group has recommended that research in the field become less fragmented and better account for patient heterogeneity and the complexity of critical illness.
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06:00Immune system abnormalities that mimic those seen with autism spectrum disorders have been linked to the amyloid precursor protein (APP), reports a research team from the University of South Florida's Department of Psychiatry and the Silver Child Development Center. The study, conducted with mouse models of autism, suggests that elevated levels of an APP fragment circulating in the blood could explain the aberrations in immune cell populations and function -- both observed in some autism patients.
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06:00Among obese individuals, having bariatric surgery was associated with a reduced long-term incidence of cardiovascular deaths and events such as heart attack and stroke, according to a study in the Jan. 4 issue of JAMA.
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06:00Imagine listening to music while carrying on a conversation with friends. This type of multi-tasking is fairly easy to do, right? That's because our brains efficiently and effectively separate the auditory signals - music to the right side; Conversation to the left. But what researchers have not been able to do in humans or animals is to see a parsing of duties at the single neuron level - until now.
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06:00
Blog - Statisticians Reveal What Makes America Happy
A statistical analysis of attitudes in the US reveals the main determinants of happiness but also suggests that interpreting the data is fraught with danger
The pursuit of happiness is a right enshrined in the Declaration of Independence. So an increasingly important question for economists, psychologists and decision-makers is the role that happiness plays in society and how toincrease it.
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06:00BUSM researchers identify novel compound to halt virus replication.
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06:00Predictions of the loss of animal and plant diversity around the world are common under models of future climate change. But a new study shows that because these climate models don't account for species competition and movement, they could grossly underestimate future extinctions.
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06:00Honey bees can become the unwitting hosts of a fly parasite that causes them to abandon their hives and die after a bout of disoriented, "zombie-like" behavior, San Francisco State University researchers have found.
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06:00Hospitals, health insurers and patients often rely on patient death rates in hospitals to compare hospital quality. Now a new study by researchers at Yale School of Medicine questions the accuracy of that widely used approach and supports measuring patient deaths over a period of 30 days from admission even after they have left the hospital.
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06:00The loss of manganese could mean that calcium does not stick to bones and could cause osteoporosis. This is the new theory put forward by researchers at the University of Castilla-La Mancha in Spain after studying deer antlers. The hypothesis published this month in the Frontiers of Bioscience journal still needs to be confirmed by the scientific community.
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06:00As a literature search for recommendations from current clinical practice guidelines of high methodological quality has shown, there is no compelling need for revision of any part of the disease management program for diabetes type 2. However, in its final report now published, IQWiG identified various aspects that could be supplemented and specified.
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06:00For the first time, a joint committee of the European Association for Echocardiography and the American Society of Echocardiography have issued recommendations on image acquisition using three-dimensional echocardiography.
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06:00Either heart failure or diabetes alone is bad enough, but oftentimes the two conditions seem to go together. Now, researchers reporting in the January Cell Metabolism appear to have found the culprit that leads from heart failure to diabetes and perhaps a novel way to break that metabolic vicious cycle.
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06:00Dartmouth Professor Ming Meng combines functional magnetic resonance imaging, computer vision, and psychophysics to elucidate left brain/right brain functional differences in image perception.
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06:00Research in the Journal of Leukocyte Biology suggests a woman's ovarian cycle plays a role in susceptibility to infection. Specifically, researchers found women are most susceptible to infection, such as Candida albicans or other sexually transmitted diseases, during ovulation than at any other time during the reproductive cycle. This natural "dip" in immunity may be to allow spermatozoa to survive the threat of an immune response so it may fertilize an egg successfully.
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06:00In emerging networks being established by inhibitory GABA neurons CSHL neuroscientists find strong evidence that the "default state" is for the cell to make tentative connections promiscuously, with almost every available partner. Surprisingly, GABA is not be involved in initial synapse formation, however, but rather in pruning them back, a process analogous to speed dating.
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06:00The first-ever published whole-genome sequences of not just one, but two supercentenarians, aged more than 114 years, reveal that both unusual and common genetic phenomena contribute to the genetic background of extreme human longevity. Data from the study -- led by researchers from the Boston University Schools of Public Health and Medicine and Boston Medical Center -- will be available to researchers around the world at the NIH data repository.
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06:00In an analysis of data from more than 15 countries that included the US, Canada, Australia, and many European nations, patients in the US who experienced a ST-segment elevation myocardial infarction (STEMI; a certain pattern on an electrocardiogram following a heart attack) were more likely to be readmitted to the hospital at 30 days after the heart attack than patients in other countries, according to a study in the Jan. 4 issue of JAMA.
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06:00UCLA authors discuss the importance of heart failure disease-management and early identification, as well as the treatment of body-fluid congestion, using a number of home-monitoring strategies.
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06:00We take it for granted, but the fact that our muscles grow when we work them makes them rather unique. Now, researchers have identified a key ingredient needed for that bulking up to take place. A factor produced in working muscle fibers apparently tells surrounding muscle stem cell "higher ups" that it's time to multiply and join in, according to a study in the January Cell Metabolism, a Cell Press journal.
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06:00Hydrogen sulfide, a noxious gas that smells like rotten eggs, may have beneficial effects in the kidney. Researchers at The University of Texas Health Science Center San Antonio found that this gas diminishes high glucose-induced production of scarring proteins in kidney cells. Considerable work remains to be done before studies can move to animal models.
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06:00Identifying species, separating out closely related species and managing each type on its own, is an important part of any animal management system. Some species, like the two types of two-toed sloth, are so close in appearance and behavior that differentiation can be challenging. Conservation researchers at San Diego Zoo Global's Institute of Conservation Research have developed a mechanism for identifying these reclusive species from each other.
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06:00In 1766, Frenchwoman Jeanne Baret disguised herself as a man to work as assistant botanist on the first French circumnavigation of the globe. Though Baret helped to collect over 6,000 specimens, she was left without anything in the natural world to commemorate her name. That is now to change as University of Utah biologist Eric Tepe names his newly discovered species -- a relative of the potato, Solanum baretiae. The study is published in the open-access journal PhytoKeys.
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06:00Stroke specialist Anna Barrett, M.D., of Kessler Foundation reports a collaborative study showing that bedside clinical evaluation can be optimized to diagnose spatial neglect, a disabling disorder that impedes recovery after stroke. Often overlooked, it is associated with prolonged hospital stays, accidents, falls, safety problems and chronic functional disability. Early recognition and targeted cognitive rehabilitation may improve outcomes for the 30-50 percent of stroke survivors with this hidden disability that can be more disabling than paralysis.
Naposledy aktualizované zdroje
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PhysOrg (dnes, 12:24)
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Yahoo! (dnes, 12:12)
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Guardian Unlimited Science (dnes, 12:00)
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BBC Science/Nature (dnes, 10:02)
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NYT > Science (dnes, 07:07)
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ScienceDaily (dnes, 03:53)
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ScienceNOW (dnes, 01:12)
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National Geographic News (dnes, 00:48)
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Sci-Tech Today (24. 5, 23:45)
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CBC - Technology & Science News (24. 5, 22:49)
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Discovery (24. 5, 22:06)
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NASA (24. 5, 21:35)
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TIME (23. 5, 08:40)
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