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With just 1 enzyme missing, mice show 'global' metabolic improvements
2. 3 2010 (06:00)
When researchers created mice lacking an enzyme that breaks down and releases stored triglycerides, they expected to see animals with better lipid profiles. But according to a report in the March Cell Metabolism, a Cell Press publication, they got more than they bargained for. The triacylglycerol hydrolase (TGH)-deficient mice showed global metabolic benefits, with essentially no downside.
