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Yeast unravels effects of chemotherapy drugs
9. 9 2009 (06:00)
Until now, the mode of action of nitrogen-containing bisphosphonate (N-BP) cancer drugs, used to relieve bone pain and to prevent skeletal complications in bone metastasis, has been almost entirely unknown. Researchers writing in BioMed Central's open-access journal Genome Biology have used "barcoded" yeast mutants to identify new biological processes involved in the cellular response to N-BPs, opening up opportunities for the development of new anticancer drugs.
